The APC5 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ANAPC5. This antibody recognizes Human antigen. The APC5 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains